Temozolomide Capsules 100 mg
Active Ingredient: Each capsule contains 100 mg of Temozolomide, an oral alkylating agent used in cancer treatment.
Purpose:
- Antitumor Agent: Primarily used in the treatment of specific types of brain tumors, particularly glioblastoma multiforme and anaplastic astrocytoma.
Uses:
Temozolomide is effective in managing various conditions, including:
- Glioblastoma Multiforme:
- Used in adults with newly diagnosed glioblastoma multiforme, often in combination with radiotherapy.
- Recurrent Brain Tumors:
- Effective for patients whose brain tumors have returned or worsened after initial treatment.
- Malignant Glioma:
- Utilized in the treatment of malignant gliomas, including anaplastic astrocytoma.
Mechanism of Action:
- Temozolomide works by alkylating DNA, which interferes with the cancer cell's ability to divide and grow. This leads to cell death, particularly in rapidly dividing tumor cells.
Dosage:
- Recommended Use: The typical dosage is determined by the healthcare provider based on the patient's condition. It is usually administered as follows:
- 100 mg taken orally once daily for 5 consecutive days in a 28-day cycle. The dosage may be adjusted based on the patient's response and tolerance.
Important Considerations:
- Side Effects: Common side effects may include:
- Nausea and vomiting
- Fatigue
- Hair loss
- Low blood cell counts (which can increase the risk of infection)
- Contraindications: Not suitable for patients with:
- Known hypersensitivity to Temozolomide or any of its components
- Severe bone marrow suppression
- Warnings: Caution is advised in patients with:
- A history of blood disorders
- Liver or kidney impairment
Storage:
- Store in a cool, dry place away from direct sunlight and out of reach of children.
Temozolomide is a crucial option in the management of certain brain cancers, providing significant benefits in improving patient outcomes. Always consult with a healthcare professional for personalized advice and treatment plans.