Hydroxyurea Capsules 500 mg
Active Ingredient: Each capsule contains 500 mg of Hydroxyurea, an antineoplastic agent.
Purpose:
- Anticancer and Sickle Cell Disease Treatment: Hydroxyurea is primarily used to treat certain types of cancers and manage sickle cell anemia.
Uses:
Hydroxyurea is effective in managing various conditions, including:
- Chronic Myeloid Leukemia (CML):
- Used as part of the treatment regimen for patients with this type of blood cancer.
- Head and Neck Cancers:
- Often utilized in combination with other therapies to enhance treatment efficacy.
- Sickle Cell Anemia:
- Helps reduce the frequency of painful crises and the need for blood transfusions in patients with this condition.
- Other Cancers:
- May be used in the treatment of other malignancies as determined by a healthcare provider.
Mechanism of Action:
- Hydroxyurea works by inhibiting DNA synthesis in cancer cells, leading to cell death. It also increases fetal hemoglobin levels in patients with sickle cell anemia, which helps reduce the sickling of red blood cells.
Dosage:
- Recommended Use: The typical dosage is determined by the healthcare provider based on the specific condition being treated. It is usually administered orally, with a common regimen being 500 mg taken once daily. Dosage may be adjusted based on the patient's response and tolerance.
Important Considerations:
- Side Effects: Common side effects may include:
- Nausea and vomiting
- Fatigue
- Low blood cell counts (which can increase the risk of infection)
- Skin rash
- Contraindications: Not suitable for patients with:
- Known hypersensitivity to Hydroxyurea or any of its components
- Severe bone marrow suppression
- Warnings: Caution is advised in patients with:
- A history of blood disorders
- Liver or kidney impairment
Storage:
- Store in a cool, dry place away from direct sunlight and out of reach of children.
Hydroxyurea is a vital option in the management of certain cancers and sickle cell disease, providing significant benefits in improving patient outcomes. Always consult with a healthcare professional for personalized advice and treatment plans.