Etoposide 100 mg Capsules

Active Ingredient: Each capsule contains 100 mg of Etoposide, a semisynthetic derivative of podophyllotoxin.

Purpose:

• Anticancer Agent: Etoposide is primarily used in the treatment of various types of cancer, particularly those that are resistant to other treatments.

Uses:

Etoposide is effective in managing several types of cancer, including:

1. Testicular Cancer:
   • Used in combination with other chemotherapeutic agents for the treatment of recurrent or refractory testicular cancer in adults.
2. Small Cell Lung Cancer:
   • Commonly prescribed for patients with small cell lung cancer, often in combination with other medications.
3. Blood Cancers:
   • Utilized in the treatment of certain types of leukemia and lymphoma.
4. Ovarian Cancer:
   • Sometimes used in the treatment of ovarian cancer, particularly in advanced stages.

Mechanism of Action:

• Etoposide works by inhibiting the enzyme topoisomerase II, which is crucial for DNA replication in cancer cells. This inhibition leads to DNA damage and ultimately results in the death of rapidly dividing cancer cells.

Dosage:

• Recommended Use: The typical dosage is determined by the healthcare provider based on the type of cancer and the patient's overall health. It is usually administered intravenously or orally, with a common regimen being 50 mg/m² of body surface area, given in cycles.

Important Considerations:

• Side Effects: Common side effects may include:
  • Nausea and vomiting
  • Hair loss
  • Low blood cell counts (which can increase the risk of infection)
  • Fatigue
• Contraindications: Not suitable for patients with:
  • Known hypersensitivity to Etoposide or any of its components
  • Severe bone marrow suppression
• Warnings: Caution is advised in patients with:
  • Liver or kidney impairment
  • A history of blood disorders

Storage:

• Store in a cool, dry place away from direct sunlight and out of reach of children.

Etoposide is a vital option in cancer treatment, providing significant benefits in managing various malignancies. Always consult with a healthcare professional for personalized advice and treatment plans.