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Combi Kit of Mifepristone 200 mg and Misoprostol 200 mcg Tablets

Composition:

Purpose:

  • Indication: This combination is indicated for the medical termination of early pregnancy up to 9 weeks (63 days) of gestation.

Mechanism of Action:

  1. Mifepristone:
    • Works by blocking the hormone progesterone, which is necessary for maintaining pregnancy.
    • Causes the uterine lining to break down, leading to the detachment of the embryo.
  2. Misoprostol:
    • Induces uterine contractions to help expel the pregnancy tissue.
    • Enhances the effectiveness of Mifepristone in terminating the pregnancy.

Dosage and Administration:

  • Mifepristone: Taken orally as a single dose of 200 mg.
  • Misoprostol: Administered 24 to 48 hours after taking Mifepristone, typically as 4 tablets of 200 mcg each, either orally as directed by a healthcare provider.

Important Considerations:

  • Contraindications: Not suitable for women with:
    • Ectopic pregnancy
    • Chronic adrenal failure
    • Coagulation disorders
    • Known hypersensitivity to any components of the kit
  • Side Effects: Common side effects may include:
    • Nausea
    • Vomiting
    • Diarrhea
    • Abdominal pain
    • Heavy bleeding

Storage:

  • Store in a cool, dry place away from direct sunlight and out of reach of children.

This Combi Kit provides a safe and effective option for the medical termination of early pregnancy. Always consult with a healthcare professional for personalized advice and treatment plans.

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